Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine.

Harrison’s is world-renowned as the most authoritative source for:

Clear, concise schemas

that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases

The physiologic and epidemiologic basis of signs and symptoms

which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow

Excellent and extensive visual support

including radiographs, clinical photos, schematics, and high-quality drawings

Updated clinical trial results and recommended guidelines

 

Coverage of both therapeutic approaches and specific treatment regimens

 

Practical clinical decision trees and algorithms

 

Organ/system-specific sections, with clinically relevant pathophysiology

and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, and general and specific approaches to therapy

Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition:

Current coverage of the diagnosis and treatment of diseases

from COVID to dementia to sepsis to multiple sclerosis to lung cancer

Updated content

that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries

More than 1000 clinical, pathological, and radiographic

photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes

Numerous atlases

featuring curated collections of important visual aspects of diagnosis and management

Updated and time-saving curation

and synthesis of established and new medical literature and studies

Clinically relevant coverage

of disease mechanics and pathophysiology, and related therapeutic mechanisms

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