The Voice of Clinical Reason Harrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text―and a superb resource for learning the art and science of clinical reasoning.
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Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and
clinical medicine, Harrison’s Principles of Internal Medicine provides the informational
foundation you need for the best patient care possible. This new edition is fully updated with timely
new chapters and essential updates across the spectrum of internal medicine.
Harrison’s is world-renowned as the most authoritative source
for:
Clear, concise schemas
that facilitate the generation of differential diagnoses to reason efficiently through complex
real world clinical cases
The physiologic and epidemiologic basis of signs and symptoms
which are covered through a wealth of unsurpassed expert guidance and linked to the
disease-specific chapters that follow
Excellent and extensive visual support
including radiographs, clinical photos, schematics, and high-quality drawings
Updated clinical trial results and recommended guidelines
Coverage of both therapeutic approaches and specific treatment regimens
Practical clinical decision trees and algorithms
Organ/system-specific sections, with clinically relevant pathophysiology
and practical clinical advice on the approach to the patient, strategies towards building a
differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of
clinical images and diagrams, current clinical guidelines, and general and specific approaches
to therapy
Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition:
Current coverage of the diagnosis and treatment of diseases
from COVID to dementia to sepsis to multiple sclerosis to lung cancer
Updated content
that reflects new approved therapeutics and new practice-changing guidelines and evidence
summaries
More than 1000 clinical, pathological, and radiographic
photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams
describing pathophysiologic processes
Numerous atlases
featuring curated collections of important visual aspects of diagnosis and management
Updated and time-saving curation
and synthesis of established and new medical literature and studies
Clinically relevant coverage
of disease mechanics and pathophysiology, and related therapeutic mechanisms
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