Goodman & Gilman's The Pharmacological Basis of Therapeutics

Overview

A Doody's Core Title ESSENTIAL PURCHASE!

5 STAR DOODY'S REVIEW!
"The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks....The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians."--Doody's Review Service

Table of contents

SECTION I: GENERAL PRINCIPLES
1. Pharmacokinetics and Pharmacodynamics
2. Drug Transport/Drug Transporters
3. Drug Metabolism
4. Pharmacogenomics
5. Principles of Therapeutics

SECTION II: DRUGS ACTING AT SYNAPTIC AND NEUROEFFECTORJUNCTIONAL SITES
6. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems
7. Muscarinic Receptor Agonists and Antagonists
8. Anticholinesterase Agents
9. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
10. Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists
11. 5-Hydroxytryptamine (Serotonin) Receptor Agonists and Antagonists

SECTION III: DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM
12. Neurotransmission and the Central Nervous System
13. History and Principles of Anesthesiology; General Anesthetics
14. Local Anesthetics
15. The Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium
16. Hypnotics and Sedatives
17. Introduction to Psychopharmacology: Drug Therapy of Depression and Anxiety Disorders
18. Pharmacotherapy of Psychosis and Mania
19. Drugs Effective in the Therapy of the Epilepsies
20. Treatment of Central Nervous System Degenerative Disorders
21. Opioid Analgesics
22. Ethanol
23. Drug Addiction and Drug Abuse

SECTION IV: AUTACOIDS: DRUG THERAPY OF INFLAMMATION
Introduction
24. Histamine, Bradykinin, and Their Antagonists
25. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor
26. Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout
27. Drugs Used in the Treatment of Asthma

SECTION V: DRUGS AFFECTING RENAL AND CARDIOVASCULAR FUNCTION
28. Diuretics
29. Vasopressin and Other Agents Affecting the Renal Conservation of Water
30. Renin and Angiotensin
31. Drugs Used for the Treatment of Myocardial Ischemia
32. Antihypertensive Agents and the Drug Therapy of Hypertension
33. Pharmacological Treatment of Heart Failure
34. Antiarrhythmic Drugs
35. Drug Therapy for Hypercholesterolemia and Dyslipidemia

SECTION VI: DRUGS AFFECTING GASTROINTESTINAL FUNCTION
36. Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesopheageal Reflux Disease
37. Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome
38. Agents Used of Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease

SECTION VII: CHEMOTHERAPY OF PARASITIC INFECTIONS
39. Drugs Used in the Chemotherapy of Protozoal Infections: Malaria
40. Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections
41. Drugs Used in the Chemotherapy of Helminthiasis

SECTION VIII: CHEMOTHERAPY OF MICROBIAL DISEASES
42. Antimicrobial Agents: General Considerations
43. Antimicrobial Agents (Continued): Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections
44. Antimicrobial Agents: Penicillins, Cephalosporins, and Other b-Lactam Antibiotics
45. Antimicrobial Agents: The Aminoglycosides
46. Antimicrobial Agents: Protein-Synthesis Inhibitors and Miscellaneous Antibacterial Agents
47. Antimicrobial Agents (Continued): Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy
48. Antimicrobial Agents: Antifungal Agents
49. Antimicrobial Agents: Antiviral Agents (Nonretroviral)
50. Antimicrobial Agents: Antiretroviral Agents

SECTION IX: CHEMOTHERAPY OF NEOPLASTIC DISEASES
Introduction
51. Antineoplastic Agents

SECTION X: DRUGS USED FOR IMMUNOMODULATION
52. Imunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants

SECTION XI: DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS
53. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins
54. Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs

SECTION XII: HORMONES AND HORMONE ANTAGONISTS
55. Pituitary Hormones and Their Hypothalamic Releasing Factors
56. Thyroid and Antithyroid Drugs
57. Estrogens and Progestins
58. Androgens
59. Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones
60. Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas
61. Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds

SECTION XIII: DERMATOLOGY
62. Dermatological Pharmacology

SECTION XIV: OPHTHALMOLOGY
63. Ocular Pharmacology

SECTION XV: TOXICOLOGY
64. Principles of Toxicology; Treatment of Poisoning
65. Poisoning; Heavy Metals and Heavy-Metal Antagonists

APPENDICES
I. Principles of Prescription Order Writing and Patient Compliance
II. Design and Optimization of Dosage Regimens; Pharmacokinetic Data

Review quote

"There are few technical books that remain in a leadership position for 65 years. The Pharmacological Basis of Therapeutics is one. Physicians, teachers, and medical students have voted for Goodman & Gilman with their feet and with their pocketbooks for over six decades. The question is not whether this is an important and useful text, but why?...While Goodman & Gilman is no quick-read, it is surprisingly clearly written, logical and interesting. It is also an awesome realization to see how much one never knew, added to what one knew but forgot."--The Permanente Journal