Clinical Physiology of Acid-Base and Electrolyte Disorders

Overview

This superbly written text gives students, residents, and practitioners the edge in understanding the mechanisms and clinical management of acid-base disorders. Presents the core information to understand renal and electrolyte physiology, and reviews the treatment rationale for all major acid-base and electrolyte disturbances. The entire text is exhaustively revised, and now includes questions and answers in each chapter.

Table of contents

Part One: Renal Physiology.
Chapter 1: Introduction to Renal Function.
Chapter 2: Renal Circulation and Glomerular Filtration Rate.
Chapter 3: Proximal Tubule.
Chapter 4: Loop of Henle and the Countercurrent Mechanism.
Chapter 5: Functions of the Distal Nephron. Chapter 6: Effects of Hormones on Renal Function.
Part Two: Regulation of Water and Electrolyte Balance.
Chapter 7: The Total Body Water and the Plasma Sodium Concentration.
Chapter 8: Regulation of the Effective Circulating Volume.
Chapter 9: Regulation of Plasma Osmolality.
Chapter 10: Acid-Base Physiology.
Chapter 11: Regulation of Acid-Base Balance.
Chapter 12: Potassium Homeostasis.
Part Three: Physiologic Approach to Acid-Base and Electrolyte Disorders.
Chapter 13: Meaning and Application of Urine Chemistries.
Chapter 14: Hypovolemic States.
Chapter 15: Clinical Use of Diuretics.
Chapter 16: Edematous States.
Chapter 17: Introduction to Simple and Mixed Acid-Base Disorders.
Chapter 18: Metabolic Alkalosis.
Chapter 19: Metabolic Acidosis.
Chapter 20: Respiratory Acidosis.
Chapter 21: Respiratory Alkalosis.
Chapter 22: Introduction to Disorders of Osmolality.
Chapter 23: Hypoosmolal States - Hyponatremia.
Chapter 24: Hyperosmolal States - Hyponatremia.
Chapter 25: Hyperosmolal States - Hyperglycemia
Chapter 26: Introduction to Disorders of Potassium Balance.
Chapter 27: Hypokalemia.
Chapter 28: Hyperkalemia.
Chapter 29: Answers to the Problems.
Chapter 30: Summary of Equations and Formulas.

Back cover copy

“The core of information that the clinician should possess”
-- From the Preface

Like its highly acclaimed predecessors, the Fifth Edition of this classic effectively integrates the essentials of renal and electrolyte physiology with the common clinical disorders of acid-base and electrolyte balance.

FEATURES:
*An easy-to-read writing style that demystifies this difficult subject
*Basic science coverage of water and electrolyte physiology, renal physiology, and regulation of water and electrolyte balance
*Clinical chapters that quickly guide you through key points of etiology, pathophysiology, symptoms, diagnosis, and treatment of common disorders
*Crystal clear figures and handy tables that summarize key information
*End-of-chapter problems that test mastery of the material

NEW IN THIS EDITION:
*New sections on endothelin and nitric oxide
*State-of-the-art information on the properties of the calcium-sensing receptor
*Revised and expanded coverage of the neurologic sequelae of hyponatremia
*In-depth discussion of the edematous states, including heart failure, nephrotic syndrome, and cirrhosis
*Hundreds of new references