Overview
Main description
Essential light scattering theories, techniques, and practices
Extend tissue characterization and analysis capabilities using cutting-edge biophotonics tools and technologies. This comprehensive resource details the principles, devices, and procedures necessary to fully employ light scattering in clinical and diagnostic applications.
Biomedical Applications of Light Scattering explains how to work with biological scatterers and scattering codes, accurately model tissues and cells, build time-domain simulations, and resolve inverse scattering issues. Noninvasive biopsy procedures, precancer and disease screening methods, and fiber optic probe design techniques are also covered in this detailed volume.
- Analyze light scattering spectra from complex and continuous media
- Build high-resolution cellular models using FDTD and PSTD methods
- Work with confocal microscopic imaging and diffuse optical tomography
- Measure blood flow using laser Doppler, LSCI, and photon correlation
- Perform noninvasive optical biopsies using elastic scattering techniques
- Assess bulk tissue properties using differential pathlength spectroscopy
- Detect precancerous lesions using angle-resolved low-coherence interferometry
- Risk-stratify patients for colonoscopies using enhanced backscattering methods
Table of contents
Introduction – overview of classical light- scattering formalisms; Ch 1. FDTD and PSTD for modeling light scattering; Ch 2. a/LCI for detection of neoplasia; Ch 3. Enhanced backscattering spectroscopy for colon screening; Ch 4. Inverse scattering in OCT; Ch 5. Confocal LSS microscopy; Ch 6. Elastic scattering spectroscopy and optical biopsy; Ch 7. Cell ultrastructure scattering in Diffuse Optical Tomography; Ch 8. Sub-cellular light scattering for understanding photodynamic therapy; Ch 9. Light scattering in confocal reflectance microscopy; Ch 10. Dynamic light scattering for ocular diagnostics; Ch 11. Laser speckle contrast imaging of blood flow; Ch 12. Differential pathlength spectroscopy
Author comments
Adam Wax, Ph.D., is an associate professor of biomedical engineering at Duke University with a research emphasis on biophotonics.
Vadim Backman, Ph.D., is a professor of biomedical engineering at Northwestern University, where he specializes in optical imaging.
